Wang Lab at UCSF

The goal of our lab is to understand the neural mechanisms that underlie human motor control, study the pathophysiology when these circuits are disrupted in movement disorders, and restore these diseased circuits to their normal states using neuromodulation.

Learn more about our current clinical trial study: Adaptive Deep Brain Stimulation to Improve Motor and Gait Functions in Parkinson's Disease.

 

Adaptive DBS therapy
Adaptive Deep Brain Stimulation

Developing individualized adaptive DBS therapies to improve gait functions in Parkinson’s Disease.

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Schematic showing the different phases of research into optimizing DBS parameters for gait improvement
DBS Parameter Optimization for Gait Improvement

Developing a data-driven model to identify DBS setting parameters for improving gait functions in Parkinson’s disease.

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Two charts illustrative of the neural control of gait functions
Neural Control of Gait Functions in Parkinson's Disease

Exploring the neurophysiology of gait control in patients with movement disorders.

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Illustrations depicting epidural electrode leads (left) and the map of all contacts considered for analysis after bipolar referencing of channels (right).
Spinal Electrophysiology

Characterizing spinal neurophysiology of movement and sensation.

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Illustration of feedback-controlled deep brain stimulation for Parkinson's Disease, using a fully implantable neural interface
Motor Sequence Learning

Understanding the corticostriatal network dynamics of motor sequence learning in Parkinson’s Disease

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